| The Synthesis of Methylene Blue Photosensitiser Conjugated with Gold Nanoparticles |
| Paper ID : 2176-UFGNSM13-FULL (R1) |
| Authors: |
|
Hasan Kariminezhad *1, Sona Khayat Omrani2, Setareh Habibzadeh2, Maria Agheb3 1Basic Science faculty, Babol university of technology, Babol, Iran, PO.Box:47148-71167 2Babol university of Technology 3Babol university of technology |
| Abstract: |
| Nowadays, nanocarriers possess growing interest for medical usage such as photodynamic therapy. Conjunction of these nanoparticles with photosensitising drugs leads to more cellular uptake, higher photocytotoxicty, higher biocompatibility and more selectivity. Previous papers conclude that the 50 nm size nanoparticles give the highest cellular uptake for the purpose of photodynamic therapy. In this paper the gold nanoparticles were synthesized based on Turkevich–Frens method. Moreover, methylene blue as a relevant photosensitiser was conjugated to achieved AuNPs. The spectrometric results of UV-visible and Fourier Transform Infrared spectroscopy(FTIR) as well as Atomic Force Microscopy(AFM) emphasis on the presence of MB sensitizers connected to resulting 50 nm gold nanoparticles. |
| Keywords: |
| Gold nanoparticles, Methylene blue, Photooxidation |
| Status : Paper Accepted (Poster Presentation) |
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