| PEG decorated glycine capped Mn-Ferrite nanoparticles synthesized by co-precipitation method for biomedical application |
| Paper ID : 2464-UFGNSM13-FULL (R1) |
| Authors: |
|
Hooman Shokrollahi1, Gholam Hossein Yousefi2 1Electroceramics Group, Materials Science and Engineering Department, Shiraz University of Technology, Shiraz, Iran 2Nanotechnology and Drug Targeting Research Center, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran. |
| Abstract: |
| Our goal is to develop methoxy poly (ethylene glycol) (m-PEG) decorated, glycine capped magnetic nanoparticles (MNPs) with proper physicochemical characteristics including particle size and magnetic property. MNP were synthesized by a biocompatible chemical co-precipitation of Mn2+ and Fe3+ in a sodium hydroxide solution. In order to covalently modify nanoparticles surface by previously prepared m-PEG aldehyde, glycine was used as linker. X-ray diffraction analysis showed successful formation of pure nanocrystalline single phase of Mn-Ferrite and FT-IR spectroscopy approved that m-PEG and glycine were covalently bound to nanoparticles surface. Particle size study showed significant change after modification. In addition, the Vibrating sample magnetometry was done for measuring the magnetic properties (Ms: 52 emu/g) and showing the superparamagnetism behavior. |
| Keywords: |
| PEG; glycine; Mn-Ferrite; Co-precipitation |
| Status : Paper Accepted (Poster Presentation) |
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